Broad Spectrum Fragment Library fragment library FBDD unique fragment compounds general fragments Tweet In the past decade, fragment based drug design (FBDD) has risen as a new and effective approach to identify lead compounds and continues to show great promise in drug discovery. It requires the use of sensitive techniques such as X-ray crystallography to identify hits among low molecular weight fragment compounds that have a weak binding affinity to a drug target. The hit fragments could be then structurally optimized to lead compounds with high affinity and specificity. Broad Spectrum Fragment Library is a product of choice for FBDD project of any level. The library contains 1,226 high-quality fragments selected to meet top industry requirements. It provides an optimal, diverse set of compounds to be included in your next fragment screen. Features Product Sheet (PDF) Get Files Features 1,226 small molecule fragments No pan-assay interference (PAINS) compounds Compounds with reactive and toxic groups filtered out High predicted water solubility (LogS > -5) High diversity over the library Each fragment contains at least 1 aromatic or aliphatic ring Purity >90%; spectral data available Product Sheet (PDF) Product sheet with detailed description is available in PDF format Reaxense Broad Spectrum Fragment Library Get Files This library is available in structure-data file format (SDF) or other common formats such as XLS, CSV, PDF. Please contact us to obtain this library as well as information on price and delivery. Contact us The compounds are in stock for prompt delivery. Cherry-picking is available.
